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BMCBI
2006
173views more  BMCBI 2006»
13 years 8 months ago
Kernel-based distance metric learning for microarray data classification
Background: The most fundamental task using gene expression data in clinical oncology is to classify tissue samples according to their gene expression levels. Compared with tradit...
Huilin Xiong, Xue-wen Chen
BMCBI
2008
95views more  BMCBI 2008»
13 years 8 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2007
95views more  BMCBI 2007»
13 years 8 months ago
Phylogenetic tree information aids supervised learning for predicting protein-protein interaction based on distance matrices
Background: Protein-protein interactions are critical for cellular functions. Recently developed computational approaches for predicting protein-protein interactions utilize co-ev...
Roger A. Craig, Li Liao
BIBE
2001
IEEE
13 years 11 months ago
Gene Classification using Expression Profiles: A Feasibility Study
As various genome sequencing projects have already been completed or are near completion, genome researchers are shifting their focus from structural genomics to functional genomi...
Michihiro Kuramochi, George Karypis
KES
2008
Springer
13 years 7 months ago
Downsizing Multigenic Predictors of the Response to Preoperative Chemotherapy in Breast Cancer
We present a method for designing efficient multigenic predictors with few probes and its application to the prediction of the response to preoperative chemotherapy in breast cance...
René Natowicz, Roberto Incitti, Roman Rouzi...