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BIOINFORMATICS
2010
127views more  BIOINFORMATICS 2010»
15 years 4 months ago
Analyzing taxonomic classification using extensible Markov models
Motivation: As next generation sequencing is rapidly adding new genomes, their correct placement in the taxonomy needs verification. However, the current methods for confirming cl...
Rao M. Kotamarti, Michael Hahsler, Douglas Raiford...
CE
2008
128views more  CE 2008»
15 years 4 months ago
Beyond threaded discussion: Representational guidance in asynchronous collaborative learning environments
Although most online learning environments are predominately text based, researchers have argued that representational support for the conceptual structure of a problem would addr...
Daniel D. Suthers, Ravi K. Vatrapu, Richard Medina...
BMCBI
2007
110views more  BMCBI 2007»
15 years 4 months ago
Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy
Background: The design of long oligonucleotides for spotted DNA microarrays requires detailed attention to ensure their optimal performance in the hybridization process. The main ...
Guangan Hu, Manuel Llinás, Jingguang Li, Pe...
BMCBI
2005
119views more  BMCBI 2005»
15 years 4 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
BMCBI
2011
14 years 11 months ago
Flexible taxonomic assignment of ambiguous sequencing reads
Background: To characterize the diversity of bacterial populations in metagenomic studies, sequencing reads need to be accurately assigned to taxonomic units in a given reference ...
José Carlos Clemente, Jesper Jansson, Gabri...