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BMCBI
2007
174views more  BMCBI 2007»
13 years 9 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
BMCBI
2010
149views more  BMCBI 2010»
13 years 9 months ago
KID - an algorithm for fast and efficient text mining used to automatically generate a database containing kinetic information o
Background: The amount of available biological information is rapidly increasing and the focus of biological research has moved from single components to networks and even larger ...
Stephanie Heinen, Bernhard Thielen, Dietmar Schomb...
BMCBI
2008
130views more  BMCBI 2008»
13 years 9 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2008
121views more  BMCBI 2008»
13 years 9 months ago
iRefIndex: A consolidated protein interaction database with provenance
Background: Interaction data for a given protein may be spread across multiple databases. We set out to create a unifying index that would facilitate searching for these data and ...
Sabry Razick, George Magklaras, Ian M. Donaldson
BMCBI
2010
96views more  BMCBI 2010»
13 years 9 months ago
ModuleOrganizer: detecting modules in families of transposable elements
Background: Most known eukaryotic genomes contain mobile copied elements called transposable elements. In some species, these elements account for the majority of the genome seque...
Sébastien Tempel, Christine Rousseau, Fariz...
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