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BMCBI
2004
150views more  BMCBI 2004»
13 years 9 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...
EVOW
2005
Springer
14 years 3 months ago
Convergence Synthesis of Dynamic Frequency Modulation Tones Using an Evolution Strategy
This paper reports on steps that have been taken to enhance previously presented evolutionary sound matching work. In doing so, the convergence characteristics are shown to provide...
Thomas J. Mitchell, Anthony G. Pipe
BMCBI
2006
103views more  BMCBI 2006»
13 years 9 months ago
Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequili
Background: The discovery of cis-regulatory motifs still remains a challenging task even though the number of sequenced genomes is constantly growing. Computational analyses using...
Kenneth W. Berendzen, Kurt Stüber, Klaus Hart...
BMCBI
2007
148views more  BMCBI 2007»
13 years 9 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
13 years 11 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...