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BMCBI
2006
112views more  BMCBI 2006»
13 years 8 months ago
MassSorter: a tool for administrating and analyzing data from mass spectrometry experiments on proteins with known amino acid se
Background: Proteomics is the study of the proteome, and is critical to the understanding of cellular processes. Two central and related tasks of proteomics are protein identifica...
Harald Barsnes, Svein-Ole Mikalsen, Ingvar Eidhamm...
BMCBI
2006
119views more  BMCBI 2006»
13 years 8 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
IMCS
2007
144views more  IMCS 2007»
13 years 8 months ago
On the imbalance of the security problem space and its expected consequences
Purpose – This paper aims to report on the results of an analysis of the computer security problem space, to suggest the areas with highest potential for making progress in the ...
Konstantin Beznosov, Olga Beznosova
BMCBI
2005
94views more  BMCBI 2005»
13 years 8 months ago
Computational identification of strain-, species- and genus-specific proteins
Background: The identification of unique proteins at different taxonomic levels has both scientific and practical value. Strain-, species- and genus-specific proteins can provide ...
Raja Mazumder, Darren A. Natale, Sudhir Murthy, Ra...
BMCBI
2005
152views more  BMCBI 2005»
13 years 8 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer