MassSorter: a tool for administrating and analyzing data from mass spectrometry experiments on proteins with known amino acid se

Background: Proteomics is the study of the proteome, and is critical to the understanding of cellular processes. Two central and related tasks of proteomics are protein identification and protein characterization. Many small laboratories are interested in the characterization of a small number of proteins, e.g., how posttranslational modifications change under different conditions. Results: We have developed a software tool called MassSorter for administrating and analyzing data from peptide mass fingerprinting experiments on proteins with known amino acid sequences. It is meant for small scale mass spectrometry laboratories that are interested in posttranslational modifications of known proteins. Several experiments can be compared simultaneously, and the matched and unmatched peak values are clearly indicated. The hits can be sorted according to m/ z values (default) or according to the sequence of the protein. Filters defined by the user can mark autolytic protease peaks and other ...

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Harald Barsnes, Svein-Ole Mikalsen, Ingvar Eidhammer
• Keywords: BMCBI 2006, Posttranslational Modifications, Protein, Unmatched Peaks