Background: The emerging field of integrative bioinformatics provides the tools to organize and systematically analyze vast amounts of highly diverse biological data and thus allo...
Markus Fischer, Quan K. Thai, Melanie Grieb, J&uum...
A novel description of protein structure in terms of the generalized secondary structure elements (GSSE) is proposed. GSSE's are defined as fragments of the protein structure...
More and more proteins have been observed to display functions through intrinsic disorder. Such structurally flexible regions are shown to play important roles in biological proces...
Chung-Tsai Su, Tong-Ming Hsu, Chien-Yu Chen, Yu-Ye...
Successful secondary structure predictions provide a starting point for direct tertiary structure modelling, and also can significantly improve sequence analysis and sequence-stru...
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...