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BMCBI
2010
141views more  BMCBI 2010»
13 years 7 months ago
Computing and visually analyzing mutual information in molecular co-evolution
Background: Selective pressure in molecular evolution leads to uneven distributions of amino acids and nucleotides. In fact one observes correlations among such constituents due t...
Sebastian Bremm, Tobias Schreck, Patrick Boba, Ste...
BMCBI
2007
195views more  BMCBI 2007»
13 years 7 months ago
NeuroTerrain - a client-server system for browsing 3D biomedical image data sets
Background: Three dimensional biomedical image sets are becoming ubiquitous, along with the canonical atlases providing the necessary spatial context for analysis. To make full us...
Carl Gustafson, William J. Bug, Jonathan Nissanov
BMCBI
2008
133views more  BMCBI 2008»
13 years 7 months ago
ElliPro: a new structure-based tool for the prediction of antibody epitopes
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...
BMCBI
2008
152views more  BMCBI 2008»
13 years 7 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
BMCBI
2008
126views more  BMCBI 2008»
13 years 7 months ago
NITPICK: peak identification for mass spectrometry data
Background: The reliable extraction of features from mass spectra is a fundamental step in the automated analysis of proteomic mass spectrometry (MS) experiments. Results: This co...
Bernhard Y. Renard, Marc Kirchner, Hanno Steen, Ju...