Creating comprehensive simulation models can be expensive and time consuming. This paper discusses our efforts to develop a general methodology that will allow users to quickly an...
Interactions that determinecellular fate are exceedingly complex, can take place at different levels of gene regulation and involve a large numberof components(such as genes, prot...
Service-oriented systems are becoming more and more nodes in a digital, dynamic ecosystem requiring the identification and establishment of flexible, spontaneous collaboration act...
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...