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BMCBI
2005
133views more  BMCBI 2005»
13 years 7 months ago
Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops
Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
Hélène Chiapello, I. Bourgait, F. So...
APBC
2004
13 years 9 months ago
EMAGEN: An Efficient Approach to Multiple Whole Genome Alignment
Following advances in biotechnology, many new whole genome sequences are becoming available every year. A lot of useful information can be derived from the alignment and compariso...
Jitender S. Deogun, Jingyi Yang, Fangrui Ma
GCB
2004
Springer
139views Biometrics» more  GCB 2004»
14 years 1 months ago
Graph Alignments: A New Concept to Detect Conserved Regions in Protein Active Sites
: We introduce the novel concept of graph alignment, a generalization of graph isomorphism that is motivated by the commonly used multiple sequence alignments. Graph alignments and...
Nils Weskamp, Eyke Hüllermeier, Daniel Kuhn, ...
BIBM
2010
IEEE
156views Bioinformatics» more  BIBM 2010»
13 years 5 months ago
Truncation of protein sequences for fast profile alignment with application to subcellular localization
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Man-Wai Mak, Wei Wang, Sun-Yuan Kung
JCB
2008
122views more  JCB 2008»
13 years 7 months ago
Space Efficient Computation of Rare Maximal Exact Matches between Multiple Sequences
In this article, we propose a new method for computing rare maximal exact matches between multiple sequences. A rare match between k sequences S1; : : :; Sk is a string that occur...
Enno Ohlebusch, Stefan Kurtz