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NAR
2010
140views more  NAR 2010»
13 years 2 months ago
GUIDANCE: a web server for assessing alignment confidence scores
Evaluating the accuracy of multiple sequence alignment (MSA) is critical for virtually every comparative sequence analysis that uses an MSA as input. Here we present the GUIDANCE ...
Osnat Penn, Eyal Privman, Haim Ashkenazy, Giddy La...
BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
BMCBI
2010
103views more  BMCBI 2010»
13 years 7 months ago
MTRAP: Pairwise sequence alignment algorithm by a new measure based on transition probability between two consecutive pairs of r
Background: Sequence alignment is one of the most important techniques to analyze biological systems. It is also true that the alignment is not complete and we have to develop it ...
Toshihide Hara, Keiko Sato, Masanori Ohya
AAAI
2004
13 years 9 months ago
PROBCONS: Probabilistic Consistency-Based Multiple Alignment of Amino Acid Sequences
Obtaining an accurate multiple alignment of protein sequences is a difficult computational problem for which many heuristic techniques sacrifice optimality to achieve reasonable r...
Chuong B. Do, Michael Brudno, Serafim Batzoglou
CJ
2008
90views more  CJ 2008»
13 years 7 months ago
Parameterized Complexity and Biopolymer Sequence Comparison
The article surveys parameterized algorithms and complexities for computational tasks on biopolymer sequences, including the problems of longest common subsequence, shortest commo...
Liming Cai, Xiuzhen Huang, Chunmei Liu, Frances A....