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BMCBI
2008
84views more  BMCBI 2008»
13 years 7 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
ICEC
1994
37views more  ICEC 1994»
13 years 9 months ago
A Method for Utilizing Diploid/Dominance in Genetic Search
homologous alleles seemingly compete prior to manifestation in the observed phenotype, will be referred to as sub-phenotype interaction.A method is proposed for implementing diploi...
F. Greene
NAR
2008
107views more  NAR 2008»
13 years 7 months ago
MutDB: update on development of tools for the biochemical analysis of genetic variation
Understanding how genetic variation affects the molecular function of gene products is an emergent area of bioinformatic research. Here, we present updates to MutDB (http://www.mu...
Arti Singh, Adebayo Olowoyeye, Peter H. Baenziger,...
ACL
2004
13 years 9 months ago
Multi-Criteria-based Active Learning for Named Entity Recognition
In this paper, we propose a multi-criteriabased active learning approach and effectively apply it to named entity recognition. Active learning targets to minimize the human annota...
Dan Shen, Jie Zhang, Jian Su, Guodong Zhou, Chew L...
CIARP
2006
Springer
13 years 11 months ago
Oscillating Feature Subset Search Algorithm for Text Categorization
Abstract. A major characteristic of text document categorization problems is the extremely high dimensionality of text data. In this paper we explore the usability of the Oscillati...
Jana Novovicová, Petr Somol, Pavel Pudil