Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
homologous alleles seemingly compete prior to manifestation in the observed phenotype, will be referred to as sub-phenotype interaction.A method is proposed for implementing diploi...
Understanding how genetic variation affects the molecular function of gene products is an emergent area of bioinformatic research. Here, we present updates to MutDB (http://www.mu...
Arti Singh, Adebayo Olowoyeye, Peter H. Baenziger,...
In this paper, we propose a multi-criteriabased active learning approach and effectively apply it to named entity recognition. Active learning targets to minimize the human annota...
Dan Shen, Jie Zhang, Jian Su, Guodong Zhou, Chew L...
Abstract. A major characteristic of text document categorization problems is the extremely high dimensionality of text data. In this paper we explore the usability of the Oscillati...