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BMCBI
2007
13 years 9 months ago
2007
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
BMCBI
2008
13 years 9 months ago
2008
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
BMCBI
2007
13 years 9 months ago
2007
Background: As a consequence of the evolutionary process, data collected from related species tend to be similar. This similarity by descent can obscure subtler signals in the dat...
BMCBI
2008
13 years 9 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
BMCBI
2010
13 years 9 months ago
2010
Background: In biological and medical domain, the use of web services made the data and computation functionality accessible in a unified manner, which helped automate the data pi...