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    BMCBI
    2007
    156views more  BMCBI 2007»
    Bio: : NEXUS: a Perl API for the NEXUS format for comparative biological data
    13 years 9 months ago
    Bio: : NEXUS: a Perl API for the NEXUS format for comparative biological data
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    Background: Evolutionary analysis provides a formal framework for comparative analysis of genomic and other data. In evolutionary analysis, observed data are treated as the termin...
    Thomas Hladish, Vivek Gopalan, Chengzhi Liang, Wei...
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    BMCBI
    2007
    134views more  BMCBI 2007»
    Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
    13 years 9 months ago
    Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
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    Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
    Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
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    BMCBI
    2008
    187views more  BMCBI 2008»
    PSAT: A web tool to compare genomic neighborhoods of multiple prokaryotic genomes
    13 years 9 months ago
    PSAT: A web tool to compare genomic neighborhoods of multiple prokaryotic genomes
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    Background: The conservation of gene order among prokaryotic genomes can provide valuable insight into gene function, protein interactions, or events by which genomes have evolved...
    Christine Fong, Laurence Rohmer, Matthew Radey, Mi...
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    BMCBI
    2007
    122views more  BMCBI 2007»
    TAP score: torsion angle propensity normalization applied to local protein structure evaluation
    13 years 9 months ago
    TAP score: torsion angle propensity normalization applied to local protein structure evaluation
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    Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
    Silvio C. E. Tosatto, Roberto Battistutta
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    BMCBI
    2010
    128views more  BMCBI 2010»
    Conserved residue clusters at protein-protein interfaces and their use in binding site identification
    13 years 9 months ago
    Conserved residue clusters at protein-protein interfaces and their use in binding site identification
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    Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
    Mainak Guharoy, Pinak Chakrabarti
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