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BMCBI
2006
13 years 9 months ago
2006
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
BMCBI
2006
13 years 9 months ago
2006
Background: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete a...
BMCBI
2006
13 years 9 months ago
2006
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
BMCBI
2006
13 years 9 months ago
2006
Background: There is an ever increasing rate of data made available on genetic variation, transcriptomes and proteomes. Similarly, a growing variety of bioinformatic programs are ...
BMCBI
2006
13 years 9 months ago
2006
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...