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BMCBI
2007
174views more  BMCBI 2007»
13 years 9 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
BMCBI
2008
242views more  BMCBI 2008»
13 years 9 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
CORR
2010
Springer
80views Education» more  CORR 2010»
13 years 9 months ago
Separations of Matroid Freeness Properties
Properties of Boolean functions on the hypercube that are invariant with respect to linear transformations of the domain are among some of the most well-studied properties in the ...
Arnab Bhattacharyya, Elena Grigorescu, Jakob Nords...
BMCBI
2006
130views more  BMCBI 2006»
13 years 9 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
COMGEO
2006
ACM
13 years 9 months ago
Computing homotopic shortest paths efficiently
Geometric shortest paths are a major topic in computational geometry; see the survey paper by Mitchell [12]. A shortest path between two points in a simple polygon can be found in...
Alon Efrat, Stephen G. Kobourov, Anna Lubiw