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» Semantics-Preserving Procedure Extraction
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BMCBI
2010
153views more  BMCBI 2010»
13 years 10 months ago
Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
Eva Freyhult, Mattias Landfors, Jenny Önskog,...
BMCBI
2007
239views more  BMCBI 2007»
13 years 10 months ago
Pre-processing Agilent microarray data
Background: Pre-processing methods for two-sample long oligonucleotide arrays, specifically the Agilent technology, have not been extensively studied. The goal of this study is to...
Marianna Zahurak, Giovanni Parmigiani, Wayne Yu, R...
BMCBI
2007
79views more  BMCBI 2007»
13 years 10 months ago
Orthology prediction at scalable resolution by phylogenetic tree analysis
Background: Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an ove...
René T. J. M. van der Heijden, Berend Snel,...
BMCBI
2006
99views more  BMCBI 2006»
13 years 9 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BMCBI
2006
144views more  BMCBI 2006»
13 years 9 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...