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» Semi-supervised Discriminant Analysis
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BMCBI
2007
194views more  BMCBI 2007»
13 years 8 months ago
Kernel-imbedded Gaussian processes for disease classification using microarray gene expression data
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
Xin Zhao, Leo Wang-Kit Cheung
BMCBI
2008
132views more  BMCBI 2008»
13 years 8 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2010
114views more  BMCBI 2010»
13 years 8 months ago
Detecting variants with Metabolic Design, a new software tool to design probes for explorative functional DNA microarray develop
Background: Microorganisms display vast diversity, and each one has its own set of genes, cell components and metabolic reactions. To assess their huge unexploited metabolic poten...
Sébastien Terrat, Eric Peyretaillade, Olivi...
BMCBI
2008
106views more  BMCBI 2008»
13 years 8 months ago
A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selec
Background: Cell viability is one of the basic properties indicating the physiological state of the cell, thus, it has long been one of the major considerations in biotechnologica...
Ning Wei, Erwin Flaschel, Karl Friehs, Tim W. Natt...
BMCBI
2008
108views more  BMCBI 2008»
13 years 8 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...