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» Sequence Complexity for Biological Sequence Analysis
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BMCBI
2010
176views more  BMCBI 2010»
13 years 9 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
BMCBI
2008
103views more  BMCBI 2008»
13 years 9 months ago
TOPS++FATCAT: Fast flexible structural alignment using constraints derived from TOPS+ Strings Model
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
Mallika Veeramalai, Yuzhen Ye, Adam Godzik
BMCBI
2008
138views more  BMCBI 2008»
13 years 9 months ago
M-BISON: Microarray-based integration of data sources using networks
Background: The accurate detection of differentially expressed (DE) genes has become a central task in microarray analysis. Unfortunately, the noise level and experimental variabi...
Bernie J. Daigle Jr., Russ B. Altman
BMCBI
2010
119views more  BMCBI 2010»
13 years 9 months ago
Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study
Background: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key...
Qi Liu, Qian Xu, Vincent Wenchen Zheng, Hong Xue, ...
BMCBI
2004
128views more  BMCBI 2004»
13 years 9 months ago
cuticleDB: a relational database of Arthropod cuticular proteins
Background: The insect exoskeleton or cuticle is a bi-partite composite of proteins and chitin that provides protective, skeletal and structural functions. Little information is a...
Christiana K. Magkrioti, Ioannis C. Spyropoulos, V...