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» Sequence Database Search Using Jumping Alignments
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BMCBI
2008
137views more  BMCBI 2008»
15 years 2 months ago
Evading the annotation bottleneck: using sequence similarity to search non-sequence gene data
Background: Non-sequence gene data (images, literature, etc.) can be found in many different public databases. Access to these data is mostly by text based methods using gene name...
Michael J. Gilchrist, Mikkel B. Christensen, Richa...
DANTE
1999
IEEE
144views Database» more  DANTE 1999»
15 years 6 months ago
Issues in Using Specifications to Improve Content-Based Search of Multimedia Data
Many current multimedia database management systems perform content-based retrieval of images by extracting the values of various features from every object stored in their system...
Leonard Brown, Le Gruenwald, Gregory D. Speegle
120
Voted
BMCBI
2007
114views more  BMCBI 2007»
15 years 2 months ago
Gene models from ESTs (GeneModelEST): an application on the Solanum lycopersicum genome
Background: The structure annotation of a genome is based either on ab initio methodologies or on similaritiy searches versus molecules that have been already annotated. Ab initio...
Nunzio D'Agostino, Alessandra Traini, Luigi Frusci...
BMCBI
2007
142views more  BMCBI 2007»
15 years 2 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
139
Voted
BMCBI
2006
143views more  BMCBI 2006»
15 years 2 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...