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BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
Huiquan Wang, Craig J. Benham
BMCBI
2005
173views more  BMCBI 2005»
13 years 7 months ago
Phydbac "Gene Function Predictor" : a gene annotation tool based on genomic context analysis
Background: The large amount of completely sequenced genomes allows genomic context analysis to predict reliable functional associations between prokaryotic proteins. Major method...
François Enault, Karsten Suhre, Jean-Michel...
BMCBI
2007
145views more  BMCBI 2007»
13 years 7 months ago
Colony size measurement of the yeast gene deletion strains for functional genomics
Background: Numerous functional genomics approaches have been developed to study the model organism yeast, Saccharomyces cerevisiae, with the aim of systematically understanding t...
Negar Memarian, Matthew Jessulat, Javad Alirezaie,...
BMCBI
2006
145views more  BMCBI 2006»
13 years 7 months ago
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
BMCBI
2004
148views more  BMCBI 2004»
13 years 7 months ago
Bioinformatics analysis of SARS coronavirus genome polymorphism
Background: We have compared 38 isolates of the SARS-CoV complete genome. The main goal was twofold: first, to analyze and compare nucleotide sequences and to identify positions o...
Gordana Pavlovic-Lazetic, Nenad S. Mitic, Milos V....