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BMCBI
2008
146views more  BMCBI 2008»
15 years 4 months ago
A phase synchronization clustering algorithm for identifying interesting groups of genes from cell cycle expression data
Background: The previous studies of genome-wide expression patterns show that a certain percentage of genes are cell cycle regulated. The expression data has been analyzed in a nu...
Chang Sik Kim, Cheol Soo Bae, Hong Joon Tcha
BMCBI
2008
117views more  BMCBI 2008»
15 years 4 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
BMCBI
2007
166views more  BMCBI 2007»
15 years 4 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
BMCBI
2007
83views more  BMCBI 2007»
15 years 4 months ago
Identification of sequence motifs significantly associated with antisense activity
Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
Kyle A. McQuisten, Andrew S. Peek
BMCBI
2008
86views more  BMCBI 2008»
15 years 4 months ago
Piecewise multivariate modelling of sequential metabolic profiling data
Background: Modelling the time-related behaviour of biological systems is essential for understanding their dynamic responses to perturbations. In metabolic profiling studies, the...
Mattias Rantalainen, Olivier Cloarec, Timothy M. D...
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