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CP
2005
Springer
14 years 1 months ago
Applying Constraint Programming to Rigid Body Protein Docking
In this paper we show how Constraint Programming (CP) techniques can improve the efficiency and applicability of grid-based algorithms for optimising surface contact between comple...
Ludwig Krippahl, Pedro Barahona
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2007
97views more  BMCBI 2007»
13 years 7 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
ICPR
2008
IEEE
14 years 1 months ago
Embedding HMM's-based models in a Euclidean space: The topological hidden Markov models
One of the major limitations of HMM-based models is the inability to cope with topology: When applied to a visible observation (VO) sequence, HMM-based techniques have difficulty ...
Djamel Bouchaffra
ISBI
2008
IEEE
14 years 8 months ago
Quantitative genetic modeling of lateral ventricular shape and volume using multi-atlas fluid image alignment in twins
Despite substantial progress in measuring the 3D profile of anatomical variations in the human brain, their genetic and environmental causes remain enigmatic. We developed an auto...
Yi-Yu Chou, Natasha Lepore, Marina Barysheva, Ming...