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BMCBI
2006
107views more  BMCBI 2006»
13 years 7 months ago
Analysis of optimal phenotypic space using elementary modes as applied to Corynebacterium glutamicum
Background: Quantification of the metabolic network of an organism offers insights into possible ways of developing mutant strain for better productivity of an extracellular metab...
Kalyan Gayen, K. V. Venkatesh
BMCBI
2007
172views more  BMCBI 2007»
13 years 7 months ago
Bayesian approaches to reverse engineer cellular systems: a simulation study on nonlinear Gaussian networks
Background: Reverse engineering cellular networks is currently one of the most challenging problems in systems biology. Dynamic Bayesian networks (DBNs) seem to be particularly su...
Fulvia Ferrazzi, Paola Sebastiani, Marco Ramoni, R...
CORR
2007
Springer
130views Education» more  CORR 2007»
13 years 7 months ago
Lagrangian Relaxation for MAP Estimation in Graphical Models
Abstract— We develop a general framework for MAP estimation in discrete and Gaussian graphical models using Lagrangian relaxation techniques. The key idea is to reformulate an in...
Jason K. Johnson, Dmitry M. Malioutov, Alan S. Wil...
BMCBI
2005
156views more  BMCBI 2005»
13 years 7 months ago
A new dynamical layout algorithm for complex biochemical reaction networks
Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Katja Wegner, Ursula Kummer
BMCBI
2005
153views more  BMCBI 2005»
13 years 7 months ago
Mining published lists of cancer related microarray experiments: Identification of a gene expression signature having a critical
Background: Routine application of gene expression microarray technology is rapidly producing large amounts of data that necessitate new approaches of analysis. The analysis of a ...
Giacomo Finocchiaro, Francesco Mancuso, Heiko M&uu...