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ISMB
1994
13 years 11 months ago
An Efficient Method for Multiple Sequence Alignment
Multiple sequence alignment has been a useful methodin the study of molecular evolution and sequence-structure relationships. This paper presents a newmethodfor multiple sequence ...
Jin Kim, Sakti Pramanik
NIPS
2004
13 years 11 months ago
A Hidden Markov Model for de Novo Peptide Sequencing
De novo Sequencing of peptides is a challenging task in proteome research. While there exist reliable DNA-sequencing methods, the highthroughput de novo sequencing of proteins by ...
Bernd Fischer, Volker Roth, Joachim M. Buhmann, Jo...
BMCBI
2010
86views more  BMCBI 2010»
13 years 10 months ago
ICC-CLASS: isotopically-coded cleavable crosslinking analysis software suite
Background: Successful application of crosslinking combined with mass spectrometry for studying proteins and protein complexes requires specifically-designed crosslinking reagents...
Evgeniy V. Petrotchenko, Christoph H. Borchers
BMCBI
2010
177views more  BMCBI 2010»
13 years 10 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren
BMCBI
2008
133views more  BMCBI 2008»
13 years 10 months ago
ElliPro: a new structure-based tool for the prediction of antibody epitopes
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...