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PRIB
2010
Springer
176views Bioinformatics» more  PRIB 2010»
13 years 8 months ago
An On/Off Lattice Approach to Protein Structure Prediction from Contact Maps
Abstract. An important unsolved problem in structural bioinformatics is that of protein structure prediction (PSP), the reconstruction of a biologically plausible three-dimensional...
Stefano Teso, Cristina Di Risio, Andrea Passerini,...
BMCBI
2010
127views more  BMCBI 2010»
13 years 10 months ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
BMCBI
2004
208views more  BMCBI 2004»
13 years 10 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
RECOMB
2006
Springer
14 years 10 months ago
Assessing Significance of Connectivity and Conservation in Protein Interaction Networks
Computational and comparative analysis of protein-protein interaction (PPI) networks enable understanding of the modular organization of the cell through identification of functio...
Mehmet Koyutürk, Ananth Grama, Wojciech Szpan...
BMCBI
2010
109views more  BMCBI 2010»
13 years 10 months ago
Pripper: prediction of caspase cleavage sites from whole proteomes
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Mirva Piippo, Niina Lietzén, Olli Nevalaine...