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WABI
2004
Springer
14 years 2 months ago
A Polynomial-Time Algorithm for the Matching of Crossing Contact-Map Patterns
Abstract. Contact maps are a model to capture the core information in the structure of biological molecules, e.g., proteins. A contact map consists of an ordered set ¡ of elements...
Jens Gramm
SDM
2010
SIAM
192views Data Mining» more  SDM 2010»
13 years 10 months ago
Fast and Accurate Gene Prediction by Decision Tree Classification
Gene prediction is one of the most challenging tasks in genome analysis, for which many tools have been developed and are still evolving. In this paper, we present a novel gene pr...
Rong She, Jeffrey Shih-Chieh Chu, Ke Wang, Nanshen...
APBC
2004
166views Bioinformatics» more  APBC 2004»
13 years 10 months ago
THEMATICS is Effective for Active Site Prediction in Comparative Model Structures
THEMATICS (Theoretical Microscopic Titration Curves) is a simple, reliable computational predictor of the active sites of enzymes from structure. Our method, based on well-establi...
Ihsan A. Shehadi, Alper Uzun, Leonel F. Murga, Val...
BMCBI
2008
87views more  BMCBI 2008»
13 years 9 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
NAR
2008
138views more  NAR 2008»
13 years 9 months ago
TarO: a target optimisation system for structural biology
TarO (http://www.compbio.dundee.ac.uk/taro) offers a single point of reference for key bioinformatics analyses relevant to selecting proteins or domains for study by structural bi...
Ian M. Overton, C. A. Johannes van Niekerk, Lester...