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» Shotgun Protein Sequencing
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BMCBI
2006
94views more  BMCBI 2006»
13 years 9 months ago
Novel knowledge-based mean force potential at the profile level
Background: The development and testing of functions for the modeling of protein energetics is an important part of current research aimed at understanding protein structure and f...
Qiwen Dong, Xiaolong Wang, Lei Lin
BMCBI
2005
173views more  BMCBI 2005»
13 years 9 months ago
Phydbac "Gene Function Predictor" : a gene annotation tool based on genomic context analysis
Background: The large amount of completely sequenced genomes allows genomic context analysis to predict reliable functional associations between prokaryotic proteins. Major method...
François Enault, Karsten Suhre, Jean-Michel...
BMCBI
2010
103views more  BMCBI 2010»
13 years 9 months ago
MTRAP: Pairwise sequence alignment algorithm by a new measure based on transition probability between two consecutive pairs of r
Background: Sequence alignment is one of the most important techniques to analyze biological systems. It is also true that the alignment is not complete and we have to develop it ...
Toshihide Hara, Keiko Sato, Masanori Ohya
BMCBI
2007
130views more  BMCBI 2007»
13 years 9 months ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...
BMCBI
2006
130views more  BMCBI 2006»
13 years 9 months ago
4SALE - A tool for synchronous RNA sequence and secondary structure alignment and editing
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...
Philipp N. Seibel, Tobias Müller, Thomas Dand...