Background: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs in nucleotide as well as amino acid sequences....
Michael Beckstette, Robert Homann, Robert Giegeric...
miRBase is the central online repository for microRNA (miRNA) nomenclature, sequence data, annotation and target prediction. The current release (10.0) contains 5071 miRNA loci fr...
Sam Griffiths-Jones, Harpreet Kaur Saini, Stijn va...
Multiple sequence alignment is a fundamental problem in computational biology. Because of its notorious difficulties, aligning sequences within a constant band (c-diagonal) is a ...
Gene duplication has long been recognized as a major force in genome evolution and has recently been recognized as an important source of individual variation. For many years the o...
Jin Jun, Paul Ryvkin, Edward Hemphill, Ion I. Mand...
Abstract. Current approaches for identification and detection of transcription factor binding sites rely on an extensive set of known target genes. Here we describe a novel structu...