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BMCBI
2007
128views more  BMCBI 2007»
13 years 7 months ago
Detailed estimation of bioinformatics prediction reliability through the Fragmented Prediction Performance Plots
Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...
Oliviero Carugo
BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
HotSwap for bioinformatics: A STRAP tutorial
Background: Bioinformatics applications are now routinely used to analyze large amounts of data. Application development often requires many cycles of optimization, compiling, and...
Christoph Gille, Peter N. Robinson
BMCBI
2006
133views more  BMCBI 2006»
13 years 7 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
BMCBI
2006
161views more  BMCBI 2006»
13 years 7 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
BMCBI
2007
159views more  BMCBI 2007»
13 years 7 months ago
Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype
Background: A finite state machine manipulating information-carrying DNA strands can be used to perform autonomous molecular-scale computations at the cellular level. Results: We ...
Israel Mark Martínez-Pérez, Gong Zha...