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» Shotgun Protein Sequencing
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CIBCB
2007
IEEE
14 years 4 months ago
A Comparison of Sequence Kernels for Localization Prediction of Transmembrane Proteins
Abstract— We applied Support Vector Machines to the prediction of the subcellular localization of transmembrane proteins, and compared the performance of different sequence kerne...
Stefan Maetschke, Marcus Gallagher, Mikael Bod&eac...
INFOSCALE
2006
ACM
14 years 4 months ago
Scalable hardware accelerator for comparing DNA and protein sequences
Abstract— Comparing genetic sequences is a well-known problem in bioinformatics. Newly determined sequences are being compared to known sequences stored in databases in order to ...
Philippe Faes, Bram Minnaert, Mark Christiaens, Er...
BMCBI
2004
77views more  BMCBI 2004»
13 years 10 months ago
A structural study for the optimisation of functional motifs encoded in protein sequences
Background: A large number of PROSITE patterns select false positives and/or miss known true positives. It is possible that
Allegra Via, Manuela Helmer-Citterich
BMCBI
2008
176views more  BMCBI 2008»
13 years 10 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
BMCBI
2007
107views more  BMCBI 2007»
13 years 10 months ago
Prediction of potential drug targets based on simple sequence properties
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Qingliang Li, Luhua Lai