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BMCBI
2006
100views more  BMCBI 2006»
13 years 8 months ago
DNPTrapper: an assembly editing tool for finishing and analysis of complex repeat regions
Background: Many genome projects are left unfinished due to complex, repeated regions. Finishing is the most time consuming step in sequencing and current finishing tools are not ...
Erik Arner, Martti T. Tammi, Anh-Nhi Tran, Ellen K...
BMCBI
2007
151views more  BMCBI 2007»
13 years 8 months ago
Minimus: a fast, lightweight genome assembler
Background: Genome assemblers have grown very large and complex in response to the need for algorithms to handle the challenges of large whole-genome sequencing projects. Many of ...
Daniel D. Sommer, Arthur L. Delcher, Steven L. Sal...
IPPS
2009
IEEE
14 years 3 months ago
Accelerating error correction in high-throughput short-read DNA sequencing data with CUDA
Emerging DNA sequencing technologies open up exciting new opportunities for genome sequencing by generating read data with a massive throughput. However, produced reads are signif...
Haixiang Shi, Bertil Schmidt, Weiguo Liu, Wolfgang...
BMCBI
2010
133views more  BMCBI 2010»
13 years 8 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
CEC
2007
IEEE
14 years 18 days ago
Efficient assembling of genome fragments using genetic algorithm enhanced by heuristic search
Abstract-- Shotgun sequencing is the state-of-the-art to decode genome sequence. However this technique needs a lot of fragments. Combining those fragments correctly requires enorm...
Satoko Kikuchi, Goutam Chakraborty