249 search results - page 46 / 50 » Shotgun Sequence Assembly |
BMCBI
2007
13 years 8 months ago
2007
Background: Polyketides are secondary metabolites of microorganisms with diverse biological activities, including pharmacological functions such as antibiotic, antitumor and agroc...
BMCBI
2010
13 years 8 months ago
2010
Background: We propose a method for deriving enzymatic signatures from short read metagenomic data of unknown species. The short read data are converted to six pseudo-peptide cand...
BMCBI
2007
13 years 8 months ago
2007
Background: Cell specific gene expression is largely regulated by different combinations of transcription factors that bind cis-elements in the upstream promoter sequence. However...
BMCBI
2008
13 years 8 months ago
2008
Background: It has been repeatedly observed that gene order is rapidly lost in prokaryotic genomes. However, persistent synteny blocks are found when comparing more or less distan...
BMCBI
2008
13 years 8 months ago
2008
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...