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CSB
2005
IEEE
129views Bioinformatics» more  CSB 2005»
14 years 2 months ago
ssahaSNP A Polymorphism Detection Tool on a Whole Genome Scale
We present a software package which can detect homozygous SNPs and indels on a eukaryotic genome scale from millions of shotgun reads. Matching seeds of a few kmer words are found...
Zemin Ning, Mario Cáccamo, James C. Mulliki...
BMCBI
2008
108views more  BMCBI 2008»
13 years 8 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
CAINE
2008
13 years 10 months ago
Parallel Assembler for Fuzzy Genome Sequence Assembly
Assembly is an NP-Hard problem, which involves comparing fragments that have a time complexity of O(n2 ). This paper presents a parallel approach for sequence assembly. The parall...
Sara Nasser, Adrienne Breland, Frederick C. Harris...
BMCBI
2007
154views more  BMCBI 2007»
13 years 8 months ago
Bounds on the distribution of the number of gaps when circles and lines are covered by fragments: Theory and practical applicati
Background: The question of how a circle or line segment becomes covered when random arcs are marked off has arisen repeatedly in bioinformatics. The number of uncovered gaps is o...
John Moriarty, Julian R. Marchesi, Anthony Metcalf...
SMA
1995
ACM
132views Solid Modeling» more  SMA 1995»
14 years 4 days ago
Assembly sequencing with toleranced parts
The goal of assembly sequencing is to plan a feasible series of operations to construct a product from its individual parts. Previous research has investigated assembly sequencing...
Jean-Claude Latombe, Randall H. Wilson