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» Signal Processing in Large Systems: a New Paradigm
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BMCBI
2011
13 years 2 months ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
RECOMB
2005
Springer
14 years 8 months ago
Decomposition of Overlapping Protein Complexes: A Graph Theoretical Method for Analyzing Static and Dynamic Protein Associations
Background: Most cellular processes are carried out by multi-protein complexes, groups of proteins that bind together to perform a specific task. Some proteins form stable complex...
Elena Zotenko, Katia S. Guimarães, Raja Jot...
ICIP
2005
IEEE
14 years 10 months ago
Automatic classification of breast density
A recent trend in digital mammography are Computer-Aided Diagnosis systems, which are computerised tools designed to assist radiologists. Most of these systems are used for the au...
Arnau Oliver, Jordi Freixenet, Reyer Zwiggelaar
ICCAD
2006
IEEE
152views Hardware» more  ICCAD 2006»
14 years 5 months ago
Performance-oriented statistical parameter reduction of parameterized systems via reduced rank regression
Process variations in modern VLSI technologies are growing in both magnitude and dimensionality. To assess performance variability, complex simulation and performance models param...
Zhuo Feng, Peng Li
ISVC
2007
Springer
14 years 2 months ago
Locally Adjustable Interpolation for Meshes of Arbitrary Topology
Abstract: A new method for constructing a smooth surface that interpolates the vertices of an arbitrary mesh is presented. The mesh can be open or closed. Normals specified at ver...
Shuhua Lai, Fuhua (Frank) Cheng, Fengtao Fan