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BMCBI
2007
13 years 7 months ago
2007
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
BMCBI
2010
13 years 7 months ago
2010
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
BMCBI
2007
13 years 7 months ago
2007
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
BMCBI
2010
2010
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
13 years 7 months ago
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...
BMCBI
2010
13 years 7 months ago
2010
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...