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BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
BMCBI
2008
86views more  BMCBI 2008»
13 years 7 months ago
Subfamily specific conservation profiles for proteins based on n-gram patterns
Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...
John K. Vries, Xiong Liu
BMCBI
2007
127views more  BMCBI 2007»
13 years 7 months ago
The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments
Background: Isotope-coded affinity tags (ICAT) is a method for quantitative proteomics based on differential isotopic labeling, sample digestion and mass spectrometry (MS). The me...
Mario Cannataro, Giovanni Cuda, Marco Gaspari, Ser...
JMLR
2010
117views more  JMLR 2010»
13 years 2 months ago
Bayesian Online Learning for Multi-label and Multi-variate Performance Measures
Many real world applications employ multivariate performance measures and each example can belong to multiple classes. The currently most popular approaches train an SVM for each ...
Xinhua Zhang, Thore Graepel, Ralf Herbrich
BMCBI
2011
13 years 2 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso