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BMCBI
2005
169views more  BMCBI 2005»
13 years 9 months ago
An adaptive method for cDNA microarray normalization
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Yingdong Zhao, Ming-Chung Li, Richard Simon
JMLR
2002
137views more  JMLR 2002»
13 years 8 months ago
The Subspace Information Criterion for Infinite Dimensional Hypothesis Spaces
A central problem in learning is selection of an appropriate model. This is typically done by estimating the unknown generalization errors of a set of models to be selected from a...
Masashi Sugiyama, Klaus-Robert Müller
BIBM
2010
IEEE
286views Bioinformatics» more  BIBM 2010»
13 years 7 months ago
Evaluation of short read metagenomic assembly
Advances in sequencing technologies have equipped researchers with the ability to sequence the collective genome of entire microbial communities commonly referred to as metagenomi...
Anveshi Charuvaka, Huzefa Rangwala
TSP
2010
13 years 3 months ago
Shrinkage algorithms for MMSE covariance estimation
We address covariance estimation in the sense of minimum mean-squared error (MMSE) when the samples are Gaussian distributed. Specifically, we consider shrinkage methods which are ...
Yilun Chen, Ami Wiesel, Yonina C. Eldar, Alfred O....
BMCBI
2011
13 years 3 months ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung