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BMCBI
2007
140views more  BMCBI 2007»
13 years 9 months ago
Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
Michael Gormley, William Dampier, Adam Ertel, Bilg...
BMCBI
2008
105views more  BMCBI 2008»
13 years 9 months ago
A Bayesian method for calculating real-time quantitative PCR calibration curves using absolute plasmid DNA standards
Background: In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potenti...
Mano Sivaganesan, Shawn Seifring, Manju Varma, Ric...
BMCBI
2008
123views more  BMCBI 2008»
13 years 9 months ago
Statistical methodology for the analysis of dye-switch microarray experiments
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...
Tristan Mary-Huard, Julie Aubert, Nadera Mansouri-...
DATAMINE
2008
143views more  DATAMINE 2008»
13 years 9 months ago
Automatically countering imbalance and its empirical relationship to cost
Learning from imbalanced datasets presents a convoluted problem both from the modeling and cost standpoints. In particular, when a class is of great interest but occurs relatively...
Nitesh V. Chawla, David A. Cieslak, Lawrence O. Ha...
BMCBI
2006
198views more  BMCBI 2006»
13 years 9 months ago
Gene selection and classification of microarray data using random forest
Background: Selection of relevant genes for sample classification is a common task in most gene expression studies, where researchers try to identify the smallest possible set of ...
Ramón Díaz-Uriarte, Sara Alvarez de ...