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BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
BMCBI
2011
13 years 2 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
BMCBI
2007
168views more  BMCBI 2007»
13 years 7 months ago
Benchmarking consensus model quality assessment for protein fold recognition
Background: Selecting the highest quality 3D model of a protein structure from a number of alternatives remains an important challenge in the field of structural bioinformatics. M...
Liam J. McGuffin
CANPC
1999
Springer
13 years 12 months ago
Implementing Application-Specific Cache-Coherence Protocols in Configurable Hardware
Streamlining communication is key to achieving good performance in shared-memory parallel programs. While full hardware support for cache coherence generally offers the best perfo...
David Brooks, Margaret Martonosi
HPDC
2002
IEEE
14 years 20 days ago
A Scalable QoS-Aware Service Aggregation Model for Peer-to-Peer Computing Grids
Peer-to-peer (P2P) computing grids consist of peer nodes that communicate directly among themselves through wide-area networks and can act as both clients and servers. These syste...
Xiaohui Gu, Klara Nahrstedt