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BMCBI
2007
112views more  BMCBI 2007»
13 years 10 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BMCBI
2008
178views more  BMCBI 2008»
13 years 10 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2007
190views more  BMCBI 2007»
13 years 10 months ago
Discriminative motif discovery in DNA and protein sequences using the DEME algorithm
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
Emma Redhead, Timothy L. Bailey
BMCBI
2008
218views more  BMCBI 2008»
13 years 10 months ago
LOSITAN: A workbench to detect molecular adaptation based on a Fst-outlier method
Background: Testing for selection is becoming one of the most important steps in the analysis of multilocus population genetics data sets. Existing applications are difficult to u...
Tiago Antao, Ana Lopes, Ricardo J. Lopes, Albano B...
BMCBI
2008
82views more  BMCBI 2008»
13 years 10 months ago
Envelope: interactive software for modeling and fitting complex isotope distributions
Background: An important aspect of proteomic mass spectrometry involves quantifying and interpreting the isotope distributions arising from mixtures of macromolecules with differe...
Michael T. Sykes, James R. Williamson
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