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BMCBI
2008
204views more  BMCBI 2008»
13 years 8 months ago
EST2uni: an open, parallel tool for automated EST analysis and database creation, with a data mining web interface and microarra
Background: Expressed sequence tag (EST) collections are composed of a high number of single-pass, redundant, partial sequences, which need to be processed, clustered, and annotat...
Javier Forment, Francisco Gilabert Villamón...
BMCBI
2007
142views more  BMCBI 2007»
13 years 8 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
BMCBI
2008
97views more  BMCBI 2008»
13 years 8 months ago
Comparison study on k-word statistical measures for protein: From sequence to 'sequence space'
Background: Many proposed statistical measures can efficiently compare protein sequence to further infer protein structure, function and evolutionary information. They share the s...
Qi Dai, Tian-Ming Wang
BMCBI
2008
130views more  BMCBI 2008»
13 years 8 months ago
An enhanced partial order curve comparison algorithm and its application to analyzing protein folding trajectories
Background: Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produc...
Hong Sun, Hakan Ferhatosmanoglu, Motonori Ota, Yus...
BMCBI
2008
173views more  BMCBI 2008»
13 years 8 months ago
Gene Vector Analysis (Geneva): A unified method to detect differentially-regulated gene sets and similar microarray experiments
Background: Microarray experiments measure changes in the expression of thousands of genes. The resulting lists of genes with changes in expression are then searched for biologica...
Stephen W. Tanner, Pankaj Agarwal
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