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» Smoothing Gene Expression Using Biological Networks
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IJBRA
2010
89views more  IJBRA 2010»
13 years 6 months ago
Strategies for enhanced annotation of a microarray probe set
—We aim to determine the biological relevance of genes identified through microarray-mediated transcriptional profiling of Xenopus sensory organs and brain tissue. Genetic data...
TuShun R. Powers, Selene M. Virk, Elba E. Serrano
BMCBI
2007
168views more  BMCBI 2007»
13 years 7 months ago
Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks
Background: Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data ...
Nikolai Daraselia, Anton Yuryev, Sergei Egorov, Il...
BIOINFORMATICS
2007
117views more  BIOINFORMATICS 2007»
13 years 7 months ago
Mining biological networks for unknown pathways
Biological pathways provide significant insights on the interaction mechanisms of molecules. Presently, many essential pathways still remain unknown or incomplete for newly sequen...
Ali Cakmak, Gultekin Özsoyoglu
BMCBI
2010
129views more  BMCBI 2010»
13 years 7 months ago
Uncovering packaging features of co-regulated modules based on human protein interaction and transcriptional regulatory networks
Background: Network co-regulated modules are believed to have the functionality of packaging multiple biological entities, and can thus be assumed to coordinate many biological fu...
Lina Chen, Hong Wang, Liangcai Zhang, Wan Li, Qian...
BMCBI
2007
90views more  BMCBI 2007»
13 years 7 months ago
Gene network interconnectedness and the generalized topological overlap measure
Background: Network methods are increasingly used to represent the interactions of genes and/ or proteins. Genes or proteins that are directly linked may have a similar biological...
Andy M. Yip, Steve Horvath