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» Smoothing Gene Expression Using Biological Networks
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122
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BMCBI
2005
161views more  BMCBI 2005»
15 years 2 months ago
Non-linear mapping for exploratory data analysis in functional genomics
Background: Several supervised and unsupervised learning tools are available to classify functional genomics data. However, relatively less attention has been given to exploratory...
Francisco Azuaje, Haiying Wang, Alban Chesneau
105
Voted
NIPS
1998
15 years 4 months ago
Computational Differences between Asymmetrical and Symmetrical Networks
Symmetrically connected recurrent networks have recently been used as models of a host of neural computations. However, biological neural networks have asymmetrical connections, at...
Zhaoping Li, Peter Dayan
99
Voted
NIPS
2000
15 years 4 months ago
Stability and Noise in Biochemical Switches
Many processes in biology, from the regulation of gene expression in bacteria to memory in the brain, involve switches constructed from networks of biochemical reactions. Crucial ...
William Bialek
157
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BIBM
2009
IEEE
151views Bioinformatics» more  BIBM 2009»
15 years 9 months ago
Detection of Gene Orthology Based on Protein-Protein Interaction Networks
Abstract—Ortholog detection methods present a powerful approach for finding genes that participate in similar biological processes across different organisms, extending our unde...
Fadi Towfic, M. Heather West Greenlee, Vasant Hona...
114
Voted
BIOSYSTEMS
2007
175views more  BIOSYSTEMS 2007»
15 years 2 months ago
Alternative routes and mutational robustness in complex regulatory networks
Alternative pathways through a gene regulation network connect a regulatory molecule to its (indirect) regulatory target via different intermediate regulators. We here show for tw...
Andreas Wagner, Jeremiah Wright