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» Smoothing Gene Expression Using Biological Networks
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RAS
2008
108views more  RAS 2008»
13 years 7 months ago
Towards long-lived robot genes
Robot projects are often evolutionary dead ends, with the software and hardware they produce disappearing without trace afterwards. Common causes include dependencies on uncommon ...
Paul M. Fitzpatrick, Giorgio Metta, Lorenzo Natale
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 2 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
IPPS
2006
IEEE
14 years 1 months ago
Parallel implementation of the replica exchange molecular dynamics algorithm on Blue Gene/L
The Replica Exchange method is a popular approach for studying the folding thermodynamics of small to modest size proteins in explicit solvent, since it is easily parallelized. Ho...
Maria Eleftheriou, Aleksandr Rayshubskiy, Jed W. P...
RECOMB
2004
Springer
14 years 8 months ago
The Statistical Significance of Max-Gap Clusters
Identifying gene clusters, genomic regions that share local similarities in gene organization, is a prerequisite for many different types of genomic analyses, including operon pred...
Rose Hoberman, David Sankoff, Dannie Durand
BMCBI
2008
159views more  BMCBI 2008»
13 years 7 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin