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» Smoothing Gene Expression Using Biological Networks
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FLAIRS
2004
13 years 10 months ago
Gene Expression Data Classification with Revised Kernel Partial Least Squares Algorithm
One important feature of the gene expression data is that the number of genes M far exceeds the number of samples N. Standard statistical methods do not work well when N < M. D...
ZhenQiu Liu, Dechang Chen
BMCBI
2005
103views more  BMCBI 2005»
13 years 8 months ago
Quadratic regression analysis for gene discovery and pattern recognition for non-cyclic short time-course microarray experiments
Background: Cluster analyses are used to analyze microarray time-course data for gene discovery and pattern recognition. However, in general, these methods do not take advantage o...
Hua Liu, Sergey Tarima, Aaron S. Borders, Thomas V...
BMCBI
2005
140views more  BMCBI 2005»
13 years 8 months ago
Dissecting systems-wide data using mixture models: application to identify affected cellular processes
Background: Functional analysis of data from genome-scale experiments, such as microarrays, requires an extensive selection of differentially expressed genes. Under many condition...
J. Peter Svensson, Renée X. de Menezes, Ing...
BMCBI
2007
157views more  BMCBI 2007»
13 years 9 months ago
Improving gene set analysis of microarray data by SAM-GS
Background: Gene-set analysis evaluates the expression of biological pathways, or a priori defined gene sets, rather than that of individual genes, in association with a binary ph...
Irina Dinu, John D. Potter, Thomas Mueller, Qi Liu...
CORR
2004
Springer
133views Education» more  CORR 2004»
13 years 8 months ago
Information theory, multivariate dependence, and genetic network inference
We define the concept of dependence among multiple variables using maximum entropy techniques and introduce a graphical notation to denote the dependencies. Direct inference of in...
Ilya Nemenman