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BMCBI
2008
13 years 9 months ago
2008
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
BMCBI
2007
13 years 9 months ago
2007
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
BMCBI
2008
13 years 9 months ago
2008
Background: Ontologies such as the Gene Ontology can enable the construction of complex queries over biological information in a conceptual way, however existing systems to do thi...
BMCBI
2007
13 years 9 months ago
2007
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
BMCBI
2007
13 years 9 months ago
2007
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...