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BMCBI
2007
111views more  BMCBI 2007»
13 years 8 months ago
Novel definition files for human GeneChips based on GeneAnnot
Background: Improvements in genome sequence annotation revealed discrepancies in the original probeset/gene assignment in Affymetrix microarray and the existence of differences be...
Francesco Ferrari, Stefania Bortoluzzi, Alessandro...
BMCBI
2010
147views more  BMCBI 2010»
13 years 8 months ago
Automatic detection of anchor points for multiple sequence alignment
Background: Determining beforehand specific positions to align (anchor points) has proved valuable for the accuracy of automated multiple sequence alignment (MSA) software. This f...
Florian Pitschi, Claudine Devauchelle, Eduardo Cor...
BMCBI
2010
128views more  BMCBI 2010»
13 years 8 months ago
VIGOR, an annotation program for small viral genomes
Background: The decrease in cost for sequencing and improvement in technologies has made it easier and more common for the re-sequencing of large genomes as well as parallel seque...
Shiliang Wang, Jaideep P. Sundaram, David Spiro
BMCBI
2010
193views more  BMCBI 2010»
13 years 8 months ago
MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data
Background: Mass spectrometry (MS) coupled with online separation methods is commonly applied for differential and quantitative profiling of biological samples in metabolomic as w...
Tomás Pluskal, Sandra Castillo, Alejandro V...
BMCBI
2007
233views more  BMCBI 2007»
13 years 8 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong