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BMCBI
2008
103views more  BMCBI 2008»
13 years 8 months ago
TOPS++FATCAT: Fast flexible structural alignment using constraints derived from TOPS+ Strings Model
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
Mallika Veeramalai, Yuzhen Ye, Adam Godzik
BMCBI
2007
153views more  BMCBI 2007»
13 years 8 months ago
MPHASYS: a mouse phenotype analysis system
Background: Systematic, high-throughput studies of mouse phenotypes have been hampered by the inability to analyze individual animal data from a multitude of sources in an integra...
R. Brent Calder, Rudolf B. Beems, Harry van Steeg,...
ECOI
2007
80views more  ECOI 2007»
13 years 8 months ago
EcoLens: Integration and interactive visualization of ecological datasets
Complex multi-dimensional datasets are now pervasive in science and elsewhere in society. Better interactive tools are needed for visual data exploration so that patterns in such ...
Cynthia Sims Parr, Bongshin Lee, Benjamin B. Beder...
BMCBI
2004
154views more  BMCBI 2004»
13 years 8 months ago
Computation of elementary modes: a unifying framework and the new binary approach
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...
Julien Gagneur, Steffen Klamt
BIOINFORMATICS
2007
190views more  BIOINFORMATICS 2007»
13 years 8 months ago
Towards clustering of incomplete microarray data without the use of imputation
Motivation: Clustering technique is used to find groups of genes that show similar expression patterns under multiple experimental conditions. Nonetheless, the results obtained by...
Dae-Won Kim, Ki Young Lee, Kwang H. Lee, Doheon Le...