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BMCBI
2007
237views more  BMCBI 2007»
13 years 9 months ago
FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data
Background: Data clustering analysis has been extensively applied to extract information from gene expression profiles obtained with DNA microarrays. To this aim, existing cluster...
Limin Fu, Enzo Medico
BMCBI
2007
127views more  BMCBI 2007»
13 years 9 months ago
The EIPeptiDi tool: enhancing peptide discovery in ICAT-based LC MS/MS experiments
Background: Isotope-coded affinity tags (ICAT) is a method for quantitative proteomics based on differential isotopic labeling, sample digestion and mass spectrometry (MS). The me...
Mario Cannataro, Giovanni Cuda, Marco Gaspari, Ser...
BMCBI
2007
95views more  BMCBI 2007»
13 years 9 months ago
ZPS: visualization of recent adaptive evolution of proteins
Background: Detection of adaptive amino acid changes in proteins under recent short-term selection is of great interest for researchers studying microevolutionary processes in mic...
Sujay Chattopadhyay, Daniel E. Dykhuizen, Evgeni V...
BMCBI
2007
168views more  BMCBI 2007»
13 years 9 months ago
GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
Holger Fröhlich, Nora Speer, Annemarie Poustk...
BMCBI
2007
166views more  BMCBI 2007»
13 years 9 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
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